陈勋，教授，博士生导师
行政职务：人工智能药物研究中心主任
科学研究方向：AI辅助药物设计/Energy Landscape Theory /多尺度的分子动力学模拟
邮箱：chenxun@njmu.edu.cn
个人简介：
主要从事结合第一性原理和人工智能的疾病多尺度时空机制和精准干预的理论研究。发展了多尺度分子动力学模型并提出能量挫折指数的计算范式，突破了现有药物设计中静态靶标的局限性，拓宽了疾病机制和药物发现的外延
奖项及荣誉：（省级及以上获奖）
Harry B. Weiser Research Award
John L. Margrave Thesis Award
学术兼职：
江苏省生物信息协会理事
全国生物分子结构预测与模拟专委
承担科研课题：（省部级以上）
2023年入选海外国家高层次青年人才
近五年代表性论文：
Chen, X., Jin, S., Liu, C. H., Levy, Y., Tsai, M. Y., & Wolynes, P. G. (2025). Intersegment Transfer and the Dynamical Architecture of Fis Protein–DNA Multimer Complexes. Journal of the American Chemical Society, 147(33), 30277-30286.
Chen, X., Jin, S., Chen, M., Bueno, C., & Wolynes, P. G. (2023). The marionette mechanism of domain–domain communication in the antagonist, agonist, and coactivator responses of the estrogen receptor. Proceedings of the National Academy of Sciences, 120(6), e2216906120.
Chen, X., Chen, M., & Wolynes, P. G. (2022). Exploring the interplay between disordered and ordered oligomer channels on the aggregation energy landscapes of α-synuclein. The Journal of Physical Chemistry B, 126(28), 5250-5261.
Chen, X., Tsai, M. Y., & Wolynes, P. G. (2022). The Role of Charge Density Coupled DNA Bending in Transcription Factor Sequence Binding Specificity: A Generic Mechanism for Indirect Readout. Journal of the American Chemical Society.
Chen, X., Chen, M. Wolynes, P. G. Pernilla, W, & Harry, G. (2022). Frustration Dynamics and Electron-Transfer Reorganization Energies in Wild-Type and Mutant Azurins. Journal of the American Chemical Society.