吕飒丽,副教授,硕士生导师
科学研究方向:生物信息学与肿瘤基因组学
电话:025-86869366
邮箱:lvsali@njmu.edu.cn
个人简介:
吕飒丽,博士,南京医科大学副教授,硕士生导师,一直从事生物信息学及相关
方向的科研与教学工作。主要研究方向为基于多组学数据挖掘肿瘤耐药机制及新
靶点发现。
教育背景及工作经历:
2002.09–2005.06 哈尔滨医科大学,生物物理学专业,硕士
2007.09–2012.06 哈尔滨医科大学,生物物理学专业,博士
2005.09–2010.08 哈尔滨医科大学,生物信息科学与技术学院,讲师
2010.09–2013.04 哈尔滨医科大学,生物信息科学与技术学院,副教授
2013.05-2018.02 南京医科大学,基础医学学院,副教授
2018.03-至今 南京医科大学,生物医学工程与信息学院,副教授
承担科研课题:(省部级以上)
1. 横向课题,2019KF0106,医学大数据分析软件开发,2020.01-2022.12,
100万,在研,主持
2.江苏省重点研发计划,BE2017733,基于液相活检及微样靶向测序的恶性胶质瘤无创早期筛查及实时复发监控,2017.07-2022.04,40万,已结题,参与
3.江苏省杰青年基金项目,BK20180036,NF1缺失介导的胶质瘤细胞招募巨噬细胞的分子途径研究,2018.01-2022.04,100万,已结题,参与
4.国家自然科学基金面上项目,81572893,基于胶质瘤干细胞的个体化放疗甲基化标记识别及其功能研究,2016.01-2019.12,57万,已结题,参与
近五年代表性论文(不超过5篇):
1. Wei Wu † , Lingxiang Wu †, Mengyan Zhu †, Ziyu Wang, Min Wu, Pengping Li, Yumin Nie, Xue Lin, Jie Hu, Eskil Eskilsson, Qh Wang *, Jiaofang Shao * and Sali Lyu * . miRNA Mediated Noise Making of 30UTR Mutations in Cancer. Genes. 2018 Nov 12;9(11):545.
2. Weiwei Duan,Liangyu Li, Xuesong Li, Mengyan Zhu, Lingxiang Wu , Wei Wu, Kening Li, Yuan Liang, Rong Ding, Wenhua You, Ziyu Wang , Bin Huang, Min Wu , Tingting Zhang, Jie Li, Yan Li , Jiaofang Shao, Changsong Lin, Pengping Li , Qianghu Wang, Shukui Wang*, Xinyi Xia* , Yu Liu*, Sali Lyu*. Association of blood glucose level and prognosis of inpatients with coexistent diabetes and COVID-19. Endocrine.2022 Jan;75(1):1-9.
3. Lei Shi †, Rong Ding †, Tingting Zhang †, Wei Wu †, Ziyu Wang, Xiuzhi Jia, Kening Li, Yuan Liang, Jie Li, Mengyan Zhu, Bin Huang, Lingxiang Wu,Min Wu, Jing Chen, Chaochen Wang, Bin Huang, Caidong Liu, Hongbing Shen, Qianghu Wang, Xinyi Xia*‡, Pengping Li*‡, Sali Lyu2,3*‡ and Ying Xiao*‡ .Comparative Characterization and Risk Stratification of Asymptomatic and Presymptomatic Patients With COVID-19.Front Immunol. 2021 Jul 9;12: 700449.
4. Sheng Yang, Jiawen Cheng, Rui Zhang, Sali Lyu , Weiwei Duan* .Metabolic dysfunction‐associated fatty liver disease and liver fibrosis: Prevalence and associated factors in the middle‐ aged and older US population.Hepatol Res. 2022 Feb;52(2):176-186.
5. Lingxiang Wu, Wei Wu, Junxia Zhang, Zheng Zhao, Liangyu Li, Mengyan Zhu, Min Wu, Fan Wu, Fengqi Zhou, Yuxin Du, Ruichao Chai, Wei Zhang, Xiaoguang Qiu, Quanzhong Liu, Ziyu Wang, Jie Li, Kening Li, Apeng Chen, Yinan Jiang, Xiangwei Xiao, Han Zou8,9, Rashmi Srivastava, Tingting Zhang, Yun Cai, Yuan Liang, Bin Huang, Ruohan Zhang, Fan Lin, Lang Hu, Xiuxing Wang, Xu Qian, Sali Lv, Baoli Hu, Siyuan Zheng, Zhibin Hu, Hongbing Shen, Yongping You*, Roel G.W. Verhaak*, Tao Jiang*, and Qianghu Wang*. Natural coevolution of tumor and immunoenvironment in glioblastoma. (Cancer Discovery, ACCEPTED, 2022 Aug,IF=38.274)